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邻氨基苯乙酮

邻氨基苯乙酮结构式
邻氨基苯乙酮结构式
品牌特惠专场
常用名 邻氨基苯乙酮 英文名 2'-Aminoacetophenone
CAS号 551-93-9 分子量 135.163
密度 1.1±0.1 g/cm3 沸点 251.8±13.0 °C at 760 mmHg
分子式 C8H9NO 熔点 20 °C
MSDS 中文版 美版 闪点 106.1±19.8 °C
符号 GHS07
GHS07
信号词 Warning

Quantitative analysis of 2-aminoacetophenone in off-flavored wines by stable isotope dilution assay.

J. AOAC Int. 79(2) , 583-6, (1996)

Isotope dilution analysis was used to quantitate 2-aminoacetophenone in wines exhibiting the so-called untypical aging off-flavor. d3-Aminoacetophenone was synthesized and used as isotopomeric internal standard. The method of quantitation was verified by seve...

Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxzaole).

J. Pharm. Sci. 98(12) , 4639-49, (2009)

Glycosylation reaction kinetics of a series of aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxazole) was compared to propose a unifying reaction mechanism. Kinetic studies were conducted in aqueous solutions containing glucose i...

Purification and characterization of 2-aminoacetophenone reductase of newly isolated Burkholderia sp. YT.

J. Biosci. Bioeng. 104(5) , 416-9, (2007)

We found that a newly isolated Burkholderia sp. produced (R)-2-amino-1-phenylethanol from 2-aminoacetophenone, showing the high stereospecificity. NADPH-dependent 2-aminoacetophenone reductase purified to homogeneity was a dimer with a molecular mass of 65,00...

Effectiveness of thirteen vertebrate repellents as rodent trigeminal stimulants.

Physiol. Behav. 60(6) , 1449-52, (1996)

Repellent chemicals are presumed to activate trigeminal neurons, including polymodal nociceptors, but few data are available that bear on this notion. In the present experiment, we assessed multi-unit and single-unit responses of neurons in the rat lingual tr...

Maternal ingestion of ortho-aminoacetophenone during gestation affects intake by offspring.

Physiol. Behav. 58(5) , 925-8, (1995)

Ingested flavor chemicals cross the placental barrier and occur in the fetal blood and amniotic fluid. This occurrence is detectable by the fetus, and can influence post parturition feeding. In the present experiment, pregnant mice were offered either 0.1% or...

Transformation of 2-aminoacetophenone to ( S) -2-amino-1-phenylethanol by Arthrobacter sulfureus.

Biotechnol. Lett. 26(16) , 1255-9, (2004)

A new isolate of Arthrobacter sulfureus , when incubated at 50 g resting cells (dry cell wt) l(-1) with 50 g glucose l(-1) and 1 g 2-aminoacetophenone l(-1) in 50 mm potassium buffer (pH 7, 4 ml) at 30 degrees C, produced ( S )-2-amino-1-phenylethanol (e.e. >...

QSAR and metabolic assessment tools in the assessment of genotoxicity.

Methods Mol. Biol. 930 , 125-62, (2013)

In this chapter, a range of computational tools for applying QSAR and grouping/read-across methods are described, and their integrated use in the computational assessment of genotoxicity is illustrated through the application of selected tools to two case-stu...

Potential sources of 2-aminoacetophenone to confound the Pseudomonas aeruginosa breath test, including analysis of a food challenge study.

J. Breath Res. 5(4) , 046002, (2011)

2-Aminoacetophenone can be detected in the breath of Pseudomonas aeruginosa colonized cystic fibrosis patients; however, low levels were also detected in a small proportion of healthy subjects. It was hypothesized that food, beverages, cosmetics or medication...

2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung.

BMC Pulm. Med. 10 , 56, (2010)

Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been identified as the microbial volatile organic compoun...

An advantageous route to oxcarbazepine (trileptal) based on palladium-catalyzed arylations free of transmetallating agents.

Org. Lett. 7(22) , 4787-9, (2005)

[reaction: see text] A new route to oxcarbazepine (Trileptal), the most widely prescribed antiepileptic drug, starting from commercially available 2'-aminoacetophenone and 1,2-dibromobenzene, is reported. The sequentially accomplished key steps are palladium-...