4-羟基哌啶
4-羟基哌啶结构式
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常用名 | 4-羟基哌啶 | 英文名 | 4-Piperidinol |
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| CAS号 | 5382-16-1 | 分子量 | 101.147 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 222.0±0.0 °C at 760 mmHg | |
| 分子式 | C5H11NO | 熔点 | 86-90 °C | |
| MSDS | 中文版 美版 | 闪点 | 107.8±0.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Synthesis of novel IP agonists via N-aminoethyl cyclic amines prepared by decarboxylative ring-opening reactions.
Molecules 17(2) , 1233-46, (2012) An efficient synthesis of a highly potent and selective IP (PGI(2) receptor) agonist that is not structurally analogous to PGI(2) is described. This synthesis is accomplished through the following key steps: Nucleophilic ring-opening of 3-(4-chlorophenyl)-oxa... |
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N- versus O-arylation of aminoalcohols: orthogonal selectivity in copper-based catalysts.
J. Am. Chem. Soc. 129 , 3490, (2007)
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The spectroscopic (FT-IR, FT-IR gas phase, FT-Raman and UV) and NBO analysis of 4-Hydroxypiperidine by density functional method.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(3) , 941-52, (2010) In this work, we report a combined experimental and theoretical study on molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine (4-HP). The FT-IR solid phase (4000-400 cm(-1)), FT-IR gas phase (5000-400 cm(-1)) and FT-Ra... |
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Investigation of 4-piperidinols as novel H3 antagonists.
Bioorg. Med. Chem. Lett. 20(21) , 6246-9, (2010) Compounds containing a substituted 4-piperidinol core have been found to be potent antagonists of the human H(3) receptor. The compounds exhibited up to a 60-fold preference for inhibiting the human H(3) receptor over the mouse and showed a low binding affini... |