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氯化4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉

氯化4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉结构式
氯化4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉结构式
品牌特惠专场
常用名 氯化4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉 英文名 DMTMM
CAS号 3945-69-5 分子量 294.73
密度 N/A 沸点 N/A
分子式 C10H19ClN4O4 熔点 110-114 °C
MSDS 中文版 美版 闪点 92.5 °C
符号 GHS05 GHS07
GHS05, GHS07
信号词 Danger

Monoclonal antibody-functionalized multilayered particles: targeting cancer cells in the presence of protein coronas.

ACS Nano 9(3) , 2876-85, (2015)

Engineered particles adsorb biomolecules (e.g., proteins) when introduced in a biological medium to form a layer called a "corona". Coronas, in particular the protein corona, play an important role in determining the surface properties of particles and their ...

Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS.

Analyst 140(2) , 467-75, (2014)

Tandem mass spectrometry (MS/MS)-based relative quantification by isobaric labeling is a useful technique to compare different metabolic expression levels in biological systems. For the first time, we have labeled primary and secondary amine-containing small ...

Peptide dimethylation: fragmentation control via distancing the dimethylamino group.

J. Am. Soc. Mass Spectrom. 25(10) , 1694-704, (2014)

Direct reductive methylation of peptides is a common method for quantitative proteomics. It is an active derivatization technique; with participation of the dimethylamino group, the derivatized peptides preferentially release intense a1 ions. The advantageous...

Reduction of molecular leaching from a gel matrix for the precisely controlled release of encapsulated molecules by light stimulus.

Chem. Pharm. Bull. 62(7) , 649-53, (2014)

We have developed a general method for controlling molecular functions using a photodegradable hydrogel; gels containing molecules made from such materials are capable of release and activation by light stimulus. As the elimination of molecular leaching from ...

Development and Evaluation of a Multiplex Microsphere Assay for Quantitation of IgG and IgA Antibodies against Neisseria meningitidis Serogroup A, C, W, and Y Polysaccharides.

Clin. Vaccine Immunol. 22 , 697-705, (2015)

We developed and evaluated a rapid and simple multiplex microsphere assay for the quantification of specific IgG and IgA antibodies against meningococcal serogroup A, C, W, and Y capsular polysaccharides in serum and saliva. Meningococcal polysaccharides were...

Selective capture of glycoproteins using lectin-modified nanoporous gold monolith.

J. Chromatogr. A. 1423 , 19-30, (2015)

The surface of nanoporous gold (np-Au) monoliths was modified via a flow method with the lectin Concanavalin A (Con A) to develop a substrate for separation and extraction of glycoproteins. Self-assembled monolayers (SAMs) of α-lipoic acid (LA) on the np-Au m...

Effect of the molecular architecture on the thermosensitive properties of chitosan-g-poly(N-vinylcaprolactam).

Carbohydr. Polym. 134 , 92-101, (2015)

A series of thermoresponsive copolymers based on chitosan-g-poly(N-vinylcaprolactam) were synthesized by amidation reaction using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride as coupling reagent. The effect of molecular architecture on t...

Physicochemical and immunological assessment of engineered pure protein particles with different redox states.

ACS Nano 9(3) , 2433-44, (2015)

The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their in...

Multifunctional Hydrogel with Good Structure Integrity, Self-Healing, and Tissue-Adhesive Property Formed by Combining Diels-Alder Click Reaction and Acylhydrazone Bond.

ACS Appl. Mater. Interfaces 7 , 24023-31, (2015)

Hydrogel, as a good cartilage tissue-engineered scaffold, not only has to possess robust mechanical property but also has to have an intrinsic self-healing property to integrate itself or the surrounding host cartilage. In this work a double cross-linked netw...

Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer.

Oncol. Rep. 34 , 1825-34, (2015)

Previous studies have demonstrated that the α5β1 integrin-mediated interaction with fibronectin (FN) occurs through the Arg-Gly-Asp (RGD) cell-binding sequence in repeat III10. Indocyanine green (ICG) is a near-infrared (NIR) optical dye that has been approve...