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(R)-(+)-3,3,3-三氟-1,2-环氧丙烷

(R)-(+)-3,3,3-三氟-1,2-环氧丙烷结构式
(R)-(+)-3,3,3-三氟-1,2-环氧丙烷结构式
品牌特惠专场
常用名 (R)-(+)-3,3,3-三氟-1,2-环氧丙烷 英文名 2-(Trifluoromethyl)oxirane
CAS号 143142-90-9 分子量 112.050
密度 1.4±0.1 g/cm3 沸点 33.5±35.0 °C at 760 mmHg
分子式 C3H3F3O 熔点 N/A
MSDS 中文版 美版 闪点 -21.3±21.8 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Danger

Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein.

J. Med. Chem. 46 , 2152, (2003)

A novel series of substituted N-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]-N-(3-phenoxyphenyl)-trifluoro-3-amino-2-propanols is described which potently and reversibly inhibit cholesteryl ester transfer protein (CETP). Starting from the initial lead 1, various sub...