1-胡椒基哌嗪
1-胡椒基哌嗪结构式
|
常用名 | 1-胡椒基哌嗪 | 英文名 | Methylenedioxybenzylpiperazine |
|---|---|---|---|---|
| CAS号 | 32231-06-4 | 分子量 | 220.268 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 330.5±0.0 °C at 760 mmHg | |
| 分子式 | C12H16N2O2 | 熔点 | 36-40 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 158.4±26.5 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Effects of benzylpiperazine derivatives on the neurotoxicity of 3,4-methylenedioxymethamphetamine in rat brain.
Brain Res. 590(1-2) , 341-4, (1992) The neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA) in rat brain was attenuated significantly by coadministration of several benzylpiperazines (p-nitrobenzylpiperazine, p-chlorobenzylpiperazine and 1-piperonylpiperazine), which were weak inhibitors ... |
|
|
A novel caffeic acid-1-piperonylpiperazine hybridization compound HBU-47 inhibits LPS-mediated inflammation in RAW264.7 macrophage cells.
Int. Immunopharmacol. 19(1) , 60-5, (2014) In the present study, we synthesized a new hybrid compound by coupling caffeic acid and 1-piperonylpiperazine. The synthetic compound, acetyl-caffeic acid-1-piperonylpiperazine (HBU-47), showed potent anti-inflammatory effects inhibiting lipopolysaccharide (L... |
|
|
Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine.
Eur. J. Pharmacol. 228(2-3) , 171-4, (1992) The effects of 1-piperonylpiperazine and N,alpha-dimethylpiperonylamine, which are weak inhibitors for [3H]5-hydroxytryptamine (5-HT) uptake, on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity were examined. The reductions of serotonergic param... |