Methylenedioxybenzylpiperazine
Methylenedioxybenzylpiperazine structure
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Common Name | Methylenedioxybenzylpiperazine | ||
|---|---|---|---|---|
| CAS Number | 32231-06-4 | Molecular Weight | 220.268 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 330.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C12H16N2O2 | Melting Point | 36-40 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 158.4±26.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Effects of benzylpiperazine derivatives on the neurotoxicity of 3,4-methylenedioxymethamphetamine in rat brain.
Brain Res. 590(1-2) , 341-4, (1992) The neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA) in rat brain was attenuated significantly by coadministration of several benzylpiperazines (p-nitrobenzylpiperazine, p-chlorobenzylpiperazine and 1-piperonylpiperazine), which were weak inhibitors ... |
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A novel caffeic acid-1-piperonylpiperazine hybridization compound HBU-47 inhibits LPS-mediated inflammation in RAW264.7 macrophage cells.
Int. Immunopharmacol. 19(1) , 60-5, (2014) In the present study, we synthesized a new hybrid compound by coupling caffeic acid and 1-piperonylpiperazine. The synthetic compound, acetyl-caffeic acid-1-piperonylpiperazine (HBU-47), showed potent anti-inflammatory effects inhibiting lipopolysaccharide (L... |
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Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine.
Eur. J. Pharmacol. 228(2-3) , 171-4, (1992) The effects of 1-piperonylpiperazine and N,alpha-dimethylpiperonylamine, which are weak inhibitors for [3H]5-hydroxytryptamine (5-HT) uptake, on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity were examined. The reductions of serotonergic param... |