2-噻吩磺酰氯
2-噻吩磺酰氯结构式
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常用名 | 2-噻吩磺酰氯 | 英文名 | 2-thienylsulfonyl chloride |
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| CAS号 | 16629-19-9 | 分子量 | 182.648 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 265.2±13.0 °C at 760 mmHg | |
| 分子式 | C4H3ClO2S2 | 熔点 | 30-32 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 114.2±19.8 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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Concerted solvent processes for common sulfonyl chloride precursors used in the synthesis of sulfonamide-based drugs.
Int. J. Mol. Sci. 9(5) , 914-25, (2008) Specific rates of solvolysis in hydroxylic solvents available for the solvolysis of 2-thiophenesulfonyl chloride and phenylmethanesulfonyl chloride are supplemented by determining the values in fluoroalcohol-containing solvents. The data sets are then correla... |
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Reaction kinetics of 3-thiophenesulfonyl chloride with anilines in methanol. Arcoria A, et al.
J. Org. Chem. 39(12) , 1689-1691, (1974)
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2-(trans-. beta.-Styrylsulfonyl)-and 2-((trans-2-phenylcyclopropyl) sulfonyl) thiophene. Goralski CT.
J. Org. Chem. 37(14) , 2354-55, (1972)
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