2-thienylsulfonyl chloride
2-thienylsulfonyl chloride structure
|
Common Name | 2-thienylsulfonyl chloride | ||
|---|---|---|---|---|
| CAS Number | 16629-19-9 | Molecular Weight | 182.648 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 265.2±13.0 °C at 760 mmHg | |
| Molecular Formula | C4H3ClO2S2 | Melting Point | 30-32 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 114.2±19.8 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
|
Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
|
|
Concerted solvent processes for common sulfonyl chloride precursors used in the synthesis of sulfonamide-based drugs.
Int. J. Mol. Sci. 9(5) , 914-25, (2008) Specific rates of solvolysis in hydroxylic solvents available for the solvolysis of 2-thiophenesulfonyl chloride and phenylmethanesulfonyl chloride are supplemented by determining the values in fluoroalcohol-containing solvents. The data sets are then correla... |
|
|
Reaction kinetics of 3-thiophenesulfonyl chloride with anilines in methanol. Arcoria A, et al.
J. Org. Chem. 39(12) , 1689-1691, (1974)
|
|
|
2-(trans-. beta.-Styrylsulfonyl)-and 2-((trans-2-phenylcyclopropyl) sulfonyl) thiophene. Goralski CT.
J. Org. Chem. 37(14) , 2354-55, (1972)
|