4-BOC-氨基哌啶结构式
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常用名 | 4-BOC-氨基哌啶 | 英文名 | 4-(N-BOC-AMINO)PIPERIDINE |
|---|---|---|---|---|
| CAS号 | 73874-95-0 | 分子量 | 200.28 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 304.8±31.0 °C at 760 mmHg | |
| 分子式 | C10H20N2O2 | 熔点 | 162-166 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 138.2±24.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.
J. Med. Chem. 49 , 2784, (2006) We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety affo... |
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Synthesis of potent oxindole CDK2 inhibitors.
Bioorg. Med. Chem. 11 , 1873-1881, (2003) A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitution afforded agents with increased potency relative to the pa... |
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Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H.
Macromolecules 39(11) , 3967-3970, (2006)
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