4-(N-BOC-AMINO)PIPERIDINE

Modify Date: 2025-08-20 15:18:11

4-(N-BOC-AMINO)PIPERIDINE Structure
4-(N-BOC-AMINO)PIPERIDINE structure
 Common Name 4-(N-BOC-AMINO)PIPERIDINE
CAS Number 73874-95-0 Molecular Weight 200.28
Density 1.0±0.1 g/cm3 Boiling Point 304.8±31.0 °C at 760 mmHg
Molecular Formula C10H20N2O2 Melting Point 162-166 °C(lit.)
MSDS Chinese USA Flash Point 138.2±24.8 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of 4-(N-BOC-AMINO)PIPERIDINE


4-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 4-Boc-aminopiperidine
Synonym More Synonyms

 4-(N-BOC-AMINO)PIPERIDINE Biological Activity

Description 4-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 4-(N-Boc-amino)piperidine 是一种有机结构单元。它已被用于合成氨基哌啶抗病毒趋化因子 (CC motif) 受体 5 (CCR5) 拮抗剂和抗菌药物。
References

[1]. Burrows, JN, Cumming, JG, Fillery, SM, et al. Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas Bioorg. Med. Chem. Lett.15(1 )25-28(2005)

[2]. Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: Broad-spectrum antibacterial agents with reduced hERG activityJ. Med . Chem.54(22)7834-7847(2011)

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 304.8±31.0 °C at 760 mmHg
Melting Point 162-166 °C(lit.)
Molecular Formula C10H20N2O2
Molecular Weight 200.28
Flash Point 138.2±24.8 °C
Exact Mass 200.152481
PSA 50.36000
LogP 1.32
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.480
InChIKey CKXZPVPIDOJLLM-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NC1CCNCC1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

1-Benzyl-4-(N-Boc-amino)piperidine structure

1-Benzyl-4-(N-B...

CAS#:73889-19-7

~98%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CRYSTALGENOMICS, INC. Patent: WO2007/52938 A1, 2007 ; Location in patent: Page/Page column 18 ; WO 2007/052938 A1
4-Amino-1-benzylpiperidine structure

4-Amino-1-benzy...

CAS#:50541-93-0

Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: US2003/162772 A1, ;
1-BOC-4-CBZ-AMINO-PIPERIDINE structure

1-BOC-4-CBZ-AMI...

CAS#:159874-20-1

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479
4-Amino-1-benzylpiperidine structure

4-Amino-1-benzy...

CAS#:50541-93-0

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: Chemical and Pharmaceutical Bulletin, , vol. 49, # 6 p. 788 - 790
Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: Journal of Medicinal Chemistry, , vol. 42, # 14 p. 2706 - 2715
4-Amino-1-benzylpiperidine structure

4-Amino-1-benzy...

CAS#:50541-93-0

Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

1-Benzyl-4-(N-Boc-amino)piperidine structure

1-Benzyl-4-(N-B...

CAS#:73889-19-7

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: US2001/51727 A1, ; US 20010051727 A1
Benzyl 4-isocyanato-1-piperidinecarboxylate structure

Benzyl 4-isocya...

CAS#:220394-91-2

~%

4-(N-BOC-AMINO)PIPERIDINE Structure

4-(N-BOC-AMINO)...

CAS#:73874-95-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

J. Med. Chem. 49 , 2784, (2006)

We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group...

Synthesis of potent oxindole CDK2 inhibitors.

Bioorg. Med. Chem. 11 , 1873-1881, (2003)

A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitutio...

Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H.

Macromolecules 39(11) , 3967-3970, (2006)

 Synonyms

2-Methyl-2-propanyl 4-amino-1-piperidinecarboxylate
Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester
MFCD00798171
methanol, 1-(1,1-dimethylethoxy)-1-(4-piperidinylimino)-, (E)-
tert-butyl N-piperidin-4-ylcarbamate
tert-butyl-piperidin-4-ylcarbamat
2-Methyl-2-propanyl 4-piperidinylcarbamate
tert-butyl piperidin-4-ylcarbamate
4-(N-BOC-AMINO)PIPERIDINE
4-(tert-Butoxycarbonyl)-aminopiperidine
4-N-BOC-Aminopiperidine
4-N-(tert-Butoxycarbonyl)aminopiperidine
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