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73874-95-0

73874-95-0 structure
73874-95-0 structure

Name 4-Boc-aminopiperidine
Synonyms 2-Methyl-2-propanyl 4-amino-1-piperidinecarboxylate
Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester
MFCD00798171
methanol, 1-(1,1-dimethylethoxy)-1-(4-piperidinylimino)-, (E)-
tert-butyl N-piperidin-4-ylcarbamate
tert-butyl-piperidin-4-ylcarbamat
2-Methyl-2-propanyl 4-piperidinylcarbamate
tert-butyl piperidin-4-ylcarbamate
4-(N-BOC-AMINO)PIPERIDINE
4-(tert-Butoxycarbonyl)-aminopiperidine
4-N-BOC-Aminopiperidine
4-N-(tert-Butoxycarbonyl)aminopiperidine
Description 4-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 4-(N-Boc-amino)piperidine 是一种有机结构单元。它已被用于合成氨基哌啶抗病毒趋化因子 (CC motif) 受体 5 (CCR5) 拮抗剂和抗菌药物。
References

[1]. Burrows, JN, Cumming, JG, Fillery, SM, et al. Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas Bioorg. Med. Chem. Lett.15(1 )25-28(2005)

[2]. Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: Broad-spectrum antibacterial agents with reduced hERG activityJ. Med . Chem.54(22)7834-7847(2011)

Density 1.0±0.1 g/cm3
Boiling Point 304.8±31.0 °C at 760 mmHg
Melting Point 162-166 °C(lit.)
Molecular Formula C10H20N2O2
Molecular Weight 200.28
Flash Point 138.2±24.8 °C
Exact Mass 200.152481
PSA 50.36000
LogP 1.32
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.480
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

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73874-95-0 structure

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Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CRYSTALGENOMICS, INC. Patent: WO2007/52938 A1, 2007 ; Location in patent: Page/Page column 18 ; WO 2007/052938 A1

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Literature: US2003/162772 A1, ;

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Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479

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Literature: Chemical and Pharmaceutical Bulletin, , vol. 49, # 6 p. 788 - 790

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Literature: Journal of Medicinal Chemistry, , vol. 42, # 14 p. 2706 - 2715

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Literature: US2001/51727 A1, ; US 20010051727 A1

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73874-95-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%