6-溴-2H-1,4-苯并恶嗪-3(4H)-酮
6-溴-2H-1,4-苯并恶嗪-3(4H)-酮结构式
|
常用名 | 6-溴-2H-1,4-苯并恶嗪-3(4H)-酮 | 英文名 | 6-Bromo-2H-1,4-benzoxazin-3(4H)-one |
|---|---|---|---|---|
| CAS号 | 24036-52-0 | 分子量 | 228.043 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 376.8±42.0 °C at 760 mmHg | |
| 分子式 | C8H6BrNO2 | 熔点 | 220-225ºC | |
| MSDS | 美版 | 闪点 | 181.7±27.9 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors.
Bioorg. Med. Chem. 15 , 5912, (2007) We report the design and synthesis of a series of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as orally bioavailable small molecule inhibitors of renin. Compounds with a 2-methyl-2-aryl substitution pattern exhibit potent renin inhibition and good permea... |
期刊文献综述：
更多...