PEG4-Ms
Names
[ CAS No. ]:
65883-12-7
[ Name ]:
PEG4-Ms
[Synonym ]:
3,6,9,12-Tetraoxa-2-thiatetradecan-14-ol,2,2-dioxide
2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl methanesulfonate
11-[(methylsulfonyl)oxy]-3,6,9-trioxaundecanol
Biological Activity
[Description]:
PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C9H20O7S
[ Molecular Weight ]:
272.31600
[ Exact Mass ]:
272.09300
[ PSA ]:
99.67000
[ LogP ]:
0.08550