Glyoxylic acid

Names

[ CAS No. ]:
298-12-4

[ Name ]:
Glyoxylic acid

[Synonym ]:
Acetic acid,oxo
Oxoacetic acid
MFCD00006958
Glyoxalic acid
glyoxylate
Oxalaldehydic acid
2-Oxoacetic acid
EINECS 206-058-5
Oxoethanoic acid
carboxyketone
Formylformic acid
Glyoxylic Acid
glyoxaldehyde
oxaldehydic acid

Biological Activity

[Description]:

NSC 27785 is an organic compound that is both an aldehyde and a carboxylic acid.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3

[ Boiling Point ]:
111 ºC

[ Melting Point ]:
-93°C

[ Molecular Formula ]:
C₂H₂O₃

[ Molecular Weight ]:
74.035

[ Flash Point ]:
111°C

[ Exact Mass ]:
74.000397

[ PSA ]:
54.37000

[ LogP ]:
-0.93

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.403

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
miscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MD4550000

CHEMICAL NAME :: Glyoxylic acid

CAS REGISTRY NUMBER :: 298-12-4

BEILSTEIN REFERENCE NO. :: 0741891

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C2-H2-O3

MOLECULAR WEIGHT :: 74.04

WISWESSER LINE NOTATION :: VHVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1500 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,217,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5852 No. of Facilities: 527 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 4281 (estimated) No. of Female Employees: 2045 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H290-H317-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310-P333 + P313

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R41;R43

[ Safety Phrases ]:
S26-S36/37/39-S45-S37/39-S24

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
MD4550000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

A kinetic study of the enhancement of solution chemiluminescence of glyoxylic acid oxidation by manganese species.

Luminescence 30 , 507-11, (2015)

In order to study the mechanism of the enhancement of solution chemiluminescence, the kinetics of the decay of the oxidant and the chemiluminescence emission were followed for oxidations by permangana...

Development of a LC-MS/MS method for the simultaneous screening of seven water-soluble vitamins in processing semi-coarse wheat flour products.

Anal. Bioanal. Chem 407(12) , 3471-9, (2015)

Wheat is the second largest crop cultivated around the world and constitutes a major part of the daily diet in Europe. It is therefore important to determine the content of micronutrient in wheat and ...

Urinary metabonomics elucidate the therapeutic mechanism of Orthosiphon stamineus in mouse crystal-induced kidney injury.

J. Ethnopharmacol. 166 , 323-32, (2015)

Orthosiphon stamineus (OS), a traditional Chinese herb, is often used for promoting urination and treating nephrolithiasis.Urolithiasis is a major worldwide public health burden due to its high incide...