1,1'-Diethyl-2,2'-carbocyanine iodide

Names

[ CAS No. ]:
605-91-4

[ Name ]:
1,1'-Diethyl-2,2'-carbocyanine iodide

[Synonym ]:
Quinolinium, 1-ethyl-2-[3- (1-ethyl-2(1H)-quinolinylidene)-1-propenyl]-, iodide
Pinacyanol Iodide
EINECS 210-099-4
MFCD00011975
Quinolinium, 1-ethyl-2-[(1E,3Z)-3-(1-ethyl-2(1H)-quinolinylidene)-1-propen-1-yl]-, iodide (1:1)
1-Ethyl-2-[3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium iodide
1-Ethyl-2-[(1E,3Z)-3-(1-ethyl-2(1H)-quinolinylidene)-1-propen-1-yl]quinolinium iodide
1-Ethyl-2-[(1E,3E)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium iodide
quinolinium, 1-ethyl-2-[(1E,3E)-3-(1-ethyl-2(1H)-quinolinylidene)-1-propen-1-yl]-, iodide (1:1)
1,1'-DIETHYL-2,2'-CARBOCYANINE IODIDE

Biological Activity

[Description]:

Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Galestian Pour A, et al. Anharmonic vibrational effects in linear and two-dimensional electronic spectra. Phys Chem Chem Phys. 2017 Sep 20;19(36):24752-24760.

Chemical & Physical Properties

[ Density]:
1.151g/cm3

[ Boiling Point ]:
527.7ºC at 760 mmHg

[ Melting Point ]:
295 °C (dec.)(lit.)

[ Molecular Formula ]:
C₂₅H₂₅IN₂

[ Molecular Weight ]:
480.384

[ Flash Point ]:
240.2ºC

[ Exact Mass ]:
480.106232

[ PSA ]:
8.81000

[ LogP ]:
1.90080

[ Index of Refraction ]:
1.685

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC3676870

CHEMICAL NAME :: Quinolinium, 1-ethyl-2-(3-(1-ethyl-2(1H)-quinolylidene)propenyl)-, iodide

CAS REGISTRY NUMBER :: 605-91-4

LAST UPDATED :: 198405

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C25-H25-N2.I

MOLECULAR WEIGHT :: 480.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,296,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,296,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 3700 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,296,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 9 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,296,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 47 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,296,1951

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331

[ Precautionary Statements ]:
P261-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
S36/37/39-S45

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
VC3676870

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Chromotropic character of bacterial acidic polysaccharides: Part II--Induction of metachromasy in cationic dye pinacyanol chloride by Klebsiella K10 capsular polysaccharide.

Indian J. Biochem. Biophys. 26(2) , 74-9, (1989)

The acidic capsular polysaccharide isolated from Klebsiella K10 exhibited chromotropic character with respect to induction of metachromasy in the cationic dye pinacyanol chloride (1-ethyl-2-[3-(1-ethy...

Chromotropic character of bacterial acidic polysaccharides: Part III--Interaction of cationic dye pinacyanol chloride with Klebsiella K15 capsular polysaccharide.

Indian J. Biochem. Biophys. 27(5) , 291-4, (1990)

Interaction of cationic dye pinacyanol chloride with the acidic capsular polysaccharide isolated from Klebsiella serotype K15 has been investigated by spectral measurements. Klebsiella K15 polysacchar...

Spectrophotometric and spectrofluorometric studies on interaction of cationic dyes with bacterial capsular polysaccharide.

Indian J. Biochem. Biophys. 35(4) , 241-6, (1998)

Interaction of Klebsiella K14 capsular polysaccharide with cationic dyes pinacyanol chloride, acridine orange and phenosafranin has been studied by spectrophotometric and spectrofluorometric technique...