CB2R/FAAH modulator-1
Modify Date: 2024-04-09 16:51:33
CB2R/FAAH modulator-1 structure
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Common Name | CB2R/FAAH modulator-1 | ||
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| CAS Number | 928892-60-8 | Molecular Weight | 361.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CB2R/FAAH modulator-1CB2R/FAAH modulator-1 is a cannabinoid type 2 receptor (CB2R) full agonist with Kis of 14.8 nM and 241.3 nM for CB2R and CB1R, respectively. CB2R/FAAH modulator-1 is a fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 4 μM. CB2R/FAAH modulator-1 decreases pro-inflammatory and increases anti-inflammatory cytokines production[1]. |
| Name | CB2R/FAAH modulator-1 |
|---|
| Description | CB2R/FAAH modulator-1 is a cannabinoid type 2 receptor (CB2R) full agonist with Kis of 14.8 nM and 241.3 nM for CB2R and CB1R, respectively. CB2R/FAAH modulator-1 is a fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 4 μM. CB2R/FAAH modulator-1 decreases pro-inflammatory and increases anti-inflammatory cytokines production[1]. |
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| Related Catalog | |
| Target |
CB2R:14.8 nM (Ki) CB2R:123.6 nM (EC50) CB1R:241.3 nM (Ki) CB1R:489 nM (EC50) |
| In Vitro | CB2R/FAAH modulator-1 (化合物 13; 10 μM; 24 小时) 减少未刺激的单核细胞和巨噬细胞中促炎细胞因子 TNFα、IFN-γ、IL-1β 和 IL6 的产生[1] . |
| References |
| Molecular Formula | C24H27NO2 |
|---|---|
| Molecular Weight | 361.48 |