GluN2B receptor modulator-1

Modify Date: 2025-09-13 15:10:08

GluN2B receptor modulator-1 structure	Common Name	GluN2B receptor modulator-1
	CAS Number	2222010-71-9	Molecular Weight	396.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅F₃N₄O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GluN2B receptor modulator-1

GluN2B receptor modulator-1 is a selective GluN2B negative allosteric modulator with an IC50 value of 31 nM.

Name	GluN2B receptor modulator-1

Description	GluN2B receptor modulator-1 is a selective GluN2B negative allosteric modulator with an IC50 value of 31 nM.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Chrovian CC, et al. Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders. J Med Chem. 2020 Sep 10;63(17):9181-9196.

Molecular Formula	C₁₇H₁₅F₃N₄O₂S
Molecular Weight	396.39

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China
Product Name: GluN2B receptor modulator-1
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