2412700-00-4

2412700-00-4 structure

Name: σ1 Receptor/μ Opioid receptor modulator 1
Chemical Name: σ1 Receptor/μ Opioid receptor modulator 1
CAS Number: 2412700-00-4
Molecular Formula: C₂₄H₃₁FN₂O₂
Molecular Weight: 398.51
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2022-08-12 05:05:45
Modify Date: 2024-01-12 10:45:11
σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) is a potent σ1 receptor antagonist and μ opioid receptor agonist with Kis of 1.86 nM and 2.1 nM, respectively.σ1 Receptor/μ Opioid receptor modulator 1 exhibits potent analgesic activity. σ1 Receptor/μ Opioid receptor modulator 1 can be used for the research of neuropathic pain[1].

Name	σ1 Receptor/μ Opioid receptor modulator 1

Description	σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) is a potent σ1 receptor antagonist and μ opioid receptor agonist with Kis of 1.86 nM and 2.1 nM, respectively.σ1 Receptor/μ Opioid receptor modulator 1 exhibits potent analgesic activity. σ1 Receptor/μ Opioid receptor modulator 1 can be used for the research of neuropathic pain[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor
References	[1]. Jiaying Xiong, et al. Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain. Eur J Med Chem. 2020 Apr 1;191:112144.

Molecular Formula	C₂₄H₃₁FN₂O₂
Molecular Weight	398.51