COX-2-IN-22

Modify Date: 2024-01-11 23:46:08

COX-2-IN-22 structure	Common Name	COX-2-IN-22
	CAS Number	2447589-08-2	Molecular Weight	484.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of COX-2-IN-22

COX-2-IN-22 (Compound 4h) is a COX-2 inhibitor with an IC50 of 8.6 µM. COX-2-IN-22 also inhibits AChE, BChE, β-Secretase, LOX-5 and DPPH with IC50 values of 2.8, 6.3, 15.3, 13.9 and 6.8 µM, respectively. COX-2-IN-22 can cross BBB[1].

Name	COX-2-IN-22

Description	COX-2-IN-22 (Compound 4h) is a COX-2 inhibitor with an IC50 of 8.6 µM. COX-2-IN-22 also inhibits AChE, BChE, β-Secretase, LOX-5 and DPPH with IC50 values of 2.8, 6.3, 15.3, 13.9 and 6.8 µM, respectively. COX-2-IN-22 can cross BBB[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	COX-2:8.6 μM (IC50) AChE:2.8 μM (IC50) BChE:6.3 μM (IC50) β-Secretase:15.3 μM (IC50) LOX-5:13.9 μM (IC50) DPPH:6.8 μM (IC50)
References	[1]. Agbo EN, et al. Synthesis of furocoumarin-stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer's disease. Bioorg Chem. 2020 Aug;101:103997.

Molecular Formula	C₂₉H₂₄O₇
Molecular Weight	484.50

COX-2-IN-22

Use of COX-2-IN-22

Names

COX-2-IN-22 Biological Activity

Chemical & Physical Properties