COX-2-IN-17

Modify Date: 2025-08-28 17:01:46

COX-2-IN-17 structure	Common Name	COX-2-IN-17
	CAS Number	2411390-10-6	Molecular Weight	414.89
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₃ClN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of COX-2-IN-17

COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase[1].

Name	COX-2-IN-17

Description	COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2:0.02 μM (IC50) COX-1:>10 μM (IC50)
References	[1]. Kumari P, et al. Modification of the lead molecule: Tryptophan and piperidine appended triazines reversing inflammation and hyeperalgesia in rats. Bioorg Med Chem. 2020 Jan 15;28(2):115246.

Molecular Formula	C₂₀H₂₃ClN₆O₂
Molecular Weight	414.89

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COX-2-IN-17

Use of COX-2-IN-17

Names

COX-2-IN-17 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.