NS 11021

Modify Date: 2025-08-25 12:19:44

NS 11021 Structure
NS 11021 structure
Common Name NS 11021
CAS Number 956014-19-0 Molecular Weight 511.24
Density 1.798±0.06 g/cm3(20 °C , 760mmHg) Boiling Point 507.5±60.0 °C (760 mmHg)
Molecular Formula C16H9BrF6N6S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of NS 11021


NS 11021 is a potent and specific Ca2-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1].

 Names

Name Thiourea, N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-
Synonym More Synonyms

 NS 11021 Biological Activity

Description NS 11021 is a potent and specific Ca2-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1].
Related Catalog
Target

Ca2+-activated big-conductance K+ Channels[1]

References

[1]. Bentzen BH,et al. The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels. Mol Pharmacol. 2007 Oct;72(4):1033-44.

 Chemical & Physical Properties

Density 1.798±0.06 g/cm3(20 °C , 760mmHg)
Boiling Point 507.5±60.0 °C (760 mmHg)
Molecular Formula C16H9BrF6N6S
Molecular Weight 511.24
Exact Mass 509.97000
PSA 110.61000
LogP 5.62170

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H413
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII

 Synonyms

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[4-bromo-2-(1H-tetrazol-5-yl)phenyl]thiourea
NS 11021
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.