NS 19504
Modify Date: 2025-08-27 02:30:32
NS 19504 structure
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Common Name | NS 19504 | ||
|---|---|---|---|---|
| CAS Number | 327062-46-4 | Molecular Weight | 269.16100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H9BrN2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NS 19504NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 µM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions[1]. |
| Name | ns19504 |
|---|---|
| Synonym | More Synonyms |
| Description | NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 µM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 11.0 µM (BK channel)[1] |
| In Vitro | NS19504 increases BK currents in freshly isolated guinea pig bladder smooth muscle cells and whole-cell. NS19504 increases the whole-cell currents response to 127 %, 194 %, 258 %, 561 % of control at a concentration of 0.32 µM, 1.0 µM, 3.2 µM and 10 µM, respectively[1]. |
| References |
| Molecular Formula | C10H9BrN2S |
|---|---|
| Molecular Weight | 269.16100 |
| Exact Mass | 267.96700 |
| PSA | 67.15000 |
| LogP | 3.65980 |
| InChIKey | HGWLTZOMQZIUBW-UHFFFAOYSA-N |
| SMILES | Nc1ncc(Cc2ccc(Br)cc2)s1 |
| 5-[(4-bromophenyl)methyl]-1,3-thiazol-2-amine |
| 2-amino-5-(4-bromobenzyl)-1,3-thiazole |