Maleimide-PEG2-NHS Ester

Modify Date: 2024-01-08 12:59:28

Maleimide-PEG2-NHS Ester Structure
Maleimide-PEG2-NHS Ester structure
Common Name Maleimide-PEG2-NHS Ester
CAS Number 955094-26-5 Molecular Weight 425.39000
Density 1.41±0.1 g/cm3 (20 °C, 760 mmHg) Boiling Point N/A
Molecular Formula C18H23N3O9 Melting Point 90.0 to 94.0 °C
MSDS Chinese USA Flash Point N/A

 Use of Maleimide-PEG2-NHS Ester


Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

 Names

Name Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
Synonym More Synonyms

 Maleimide-PEG2-NHS Ester Biological Activity

Description Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
Related Catalog
Target

Noncleavable

References

[1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.

[2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A

 Chemical & Physical Properties

Density 1.41±0.1 g/cm3 (20 °C, 760 mmHg)
Melting Point 90.0 to 94.0 °C
Molecular Formula C18H23N3O9
Molecular Weight 425.39000
Exact Mass 425.14300
PSA 148.62000
Storage condition 20°C
Water Solubility Slightly soluble (5.1 g/L) (25 ºC)

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29280000

 Synonyms

MAL-EG(2)-NHS 3-(2-(2-(3-MALEINIMIDOPROPANAMIDO)ETHOXY)ETHOXY)PROPANOIC ACID SUCCINIMIDYL ESTER
SM(PEG)2
Maleimide-NH-PEG2-CH2CH2COONHS Ester
Maleimide-PEG2-succinimidyl ester
Maleimidopropionyl-PEG2-CH2CH2COONHS Ester
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Maleimide-PEG2-NHS Ester