Bromo-PEG2-NHS ester

Modify Date: 2024-04-08 11:24:04

Bromo-PEG2-NHS ester Structure
Bromo-PEG2-NHS ester structure
Common Name Bromo-PEG2-NHS ester
CAS Number 2148295-96-7 Molecular Weight 338.15
Density N/A Boiling Point N/A
Molecular Formula C11H16BrNO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-NHS ester


Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG2-NHS ester

 Bromo-PEG2-NHS ester Biological Activity

Description Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H16BrNO6
Molecular Weight 338.15