Propargyl-PEG2-NHS ester

Modify Date: 2024-01-09 11:03:44

Propargyl-PEG2-NHS ester Structure
Propargyl-PEG2-NHS ester structure
Common Name Propargyl-PEG2-NHS ester
CAS Number 2512228-06-5 Molecular Weight 269.25
Density N/A Boiling Point N/A
Molecular Formula C12H15NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG2-NHS ester


Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG2-NHS ester

 Propargyl-PEG2-NHS ester Biological Activity

Description Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

 Chemical & Physical Properties

Molecular Formula C12H15NO6
Molecular Weight 269.25