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2148295-96-7

2148295-96-7 structure
2148295-96-7 structure
  • Name: Bromo-PEG2-NHS ester
  • Chemical Name: Bromo-PEG2-NHS ester
  • CAS Number: 2148295-96-7
  • Molecular Formula: C11H16BrNO6
  • Molecular Weight: 338.15
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-14 10:27:59
  • Modify Date: 2024-04-08 11:24:04
  • Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG2-NHS ester
Description Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H16BrNO6
Molecular Weight 338.15