1353011-78-5
1353011-78-5 structure
- Name: Bromoacetamido-PEG2-C2-NHS ester
- Chemical Name: Bromoacetamido-PEG2- NHS ester
- CAS Number: 1353011-78-5
- Molecular Formula: C13H19BrN2O7
- Molecular Weight: 395.203
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-13 19:36:26
- Modify Date: 2024-01-16 16:41:33
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Bromoacetamido-PEG2-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bromoacetamido-PEG2- NHS ester |
|---|---|
| Synonyms |
Acetamide, 2-bromo-N-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethyl]-
2-Bromo-N-[2-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]acetamide MFCD20926375 |
| Description | Bromoacetamido-PEG2-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C13H19BrN2O7 |
| Molecular Weight | 395.203 |
| Exact Mass | 394.037567 |
| LogP | -2.11 |
| Index of Refraction | 1.540 |