ABD-F
ABD-F structure
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Common Name | ABD-F | ||
|---|---|---|---|---|
| CAS Number | 91366-65-3 | Molecular Weight | 217.178 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 408.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C6H4FN3O3S | Melting Point | 145-146ºC | |
| MSDS | USA | Flash Point | 201.0±31.5 °C | |
Use of ABD-F4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor[1]. |
| Name | 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole |
|---|---|
| Synonym | More Synonyms |
| Description | 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor[1]. |
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| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 408.8±55.0 °C at 760 mmHg |
| Melting Point | 145-146ºC |
| Molecular Formula | C6H4FN3O3S |
| Molecular Weight | 217.178 |
| Flash Point | 201.0±31.5 °C |
| Exact Mass | 216.995743 |
| PSA | 107.46000 |
| LogP | 0.11 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.632 |
| Storage condition | −20°C |
| Stability | Light Sensitive |
| Water Solubility | DMSO: soluble |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 20/21/22-36/37/38 |
| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2935009090 |
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~%
ABD-F CAS#:91366-65-3 |
| Literature: Analytical Chemistry, , vol. 56, p. 2461 - 2464 |
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~19%
ABD-F CAS#:91366-65-3 |
| Literature: Toyo'oka, Toshimasa; Imai, Kazuhiro Analytical Chemistry, 1984 , vol. 56, p. 2461 - 2464 |
| Precursor 2 | |
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| DownStream 1 | |
CAS#:91366-67-5| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Quantification of glutathione in plasma samples by HPLC using 4-fluoro-7-nitrobenzofurazan as a fluorescent labeling reagent.
J. Chromatogr. Sci. 50 , 119-122, (2012) A rapid and highly sensitive high-performance liquid chromatograpy method with fluorescence detection has been developed for determination of glutathione (GSH) in human plasma. A simple pre-column der... |
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Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
J. Alzheimers Dis. 44(4) , 1323-31, (2015) Widely confirmed reports were published on association between hyperhomocysteinemia, B vitamin deficiency, oxidative stress, and amyloid-β in Alzheimer's disease (AD). Homocysteine, cysteine, cysteiny... |
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Allosteric inhibition of PTP1B activity by selective modification of a non-active site cysteine residue.
Biochemistry 44(21) , 7704-12, (2005) The fluorogenic reagent 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABDF) attenuates the functional activity of the protein tyrosine phosphatase PTP1B by reacting selectively with a single cystei... |
| 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide |
| 2,1,3-Benzoxadiazole-4-sulfonamide, 7-fluoro- |
| MFCD00036687 |