MMP2-IN-3

Modify Date: 2024-01-27 19:31:20

MMP2-IN-3 Structure
MMP2-IN-3 structure
Common Name MMP2-IN-3
CAS Number 897799-81-4 Molecular Weight 355.43
Density N/A Boiling Point N/A
Molecular Formula C23H21N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMP2-IN-3


MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8, with IC50 values of 26.6, and 32 μM, respectively[1].

 Names

Name MMP2-IN-3

 MMP2-IN-3 Biological Activity

Description MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8, with IC50 values of 26.6, and 32 μM, respectively[1].
Related Catalog
Target

MMP-9:26.6 ± 2.3 μM (IC50)

MMP-2:31 ± 5 μM (IC50)

MMP-8:32 ± 4 μM (IC50)

MMP-13:>100 μM (IC50)

References

[1]. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.

 Chemical & Physical Properties

Molecular Formula C23H21N3O
Molecular Weight 355.43
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