897799-81-4

897799-81-4 structure

Name: MMP2-IN-3
Chemical Name: MMP2-IN-3
CAS Number: 897799-81-4
Molecular Formula: C₂₃H₂₁N₃O
Molecular Weight: 355.43
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2022-08-17 21:44:55
Modify Date: 2024-01-27 19:31:20
MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8, with IC50 values of 26.6, and 32 μM, respectively[1].

Name	MMP2-IN-3

Description	MMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8, with IC50 values of 26.6, and 32 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-9:26.6 ± 2.3 μM (IC50) MMP-2:31 ± 5 μM (IC50) MMP-8:32 ± 4 μM (IC50) MMP-13:>100 μM (IC50)
References	[1]. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.

Molecular Formula	C₂₃H₂₁N₃O
Molecular Weight	355.43