Dolasetron (Mesylate hydrate)

Modify Date: 2025-08-26 18:49:55

Dolasetron (Mesylate hydrate) structure	Common Name	Dolasetron (Mesylate hydrate)
	CAS Number	878143-33-0	Molecular Weight	438.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₆N₂O₇S	Melting Point	178 °C
	MSDS	N/A	Flash Point	N/A

Use of Dolasetron (Mesylate hydrate)

Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Name	UNII-U3C8E5BWKR component QTFFGPOXNNGTGZ-BEQIPBGHSA-M
Synonym	More Synonyms

Description	Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Others
References	[1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77.

Description

Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Related Catalog

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

Research Areas >> Others

References

Melting Point	178 °C
Molecular Formula	C₂₀H₂₆N₂O₇S
Molecular Weight	438.49
PSA	137.21000
LogP	2.63480
InChIKey	QTFFGPOXNNGTGZ-RCSCTSIBSA-N
SMILES	CS(=O)(=O)O.O.O=C(OC1CC2CC3CC(C1)N2CC3=O)c1c[nH]c2ccccc12

Dolasetron (Mesylate hydrate)

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Price: $211/10mM*1mLinDMSO