SUVN-502 mesylate hydrate structure
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Common Name | SUVN-502 mesylate hydrate | ||
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CAS Number | 1791396-45-6 | Molecular Weight | 688.629 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H34BrN3O10S3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of SUVN-502 mesylate hydrateSUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical |
Name | Dimesylate Dimesylate Monohydrate |
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Synonym | More Synonyms |
Description | SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical |
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References | References 1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859. 2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430. View Related Products by Target 5-HT Receptor Alzheimer Disease |
Molecular Formula | C23H34BrN3O10S3 |
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Molecular Weight | 688.629 |
Exact Mass | 687.058960 |
Dimesylate Dimesylate Monohydrate |
1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole methanesulfonate hydrate (1:2:1) |
1H-Indole, 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-, methanesulfonate, hydrate (1:2:1) |