SUVN-502 mesylate hydrate
Modify Date: 2025-08-28 13:12:45
SUVN-502 mesylate hydrate structure
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Common Name | SUVN-502 mesylate hydrate | ||
|---|---|---|---|---|
| CAS Number | 1791396-45-6 | Molecular Weight | 688.629 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H34BrN3O10S3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SUVN-502 mesylate hydrateSUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical |
| Name | Dimesylate Dimesylate Monohydrate |
|---|---|
| Synonym | More Synonyms |
| Description | SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical |
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| References | References 1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859. 2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430. View Related Products by Target 5-HT Receptor Alzheimer Disease |
| Molecular Formula | C23H34BrN3O10S3 |
|---|---|
| Molecular Weight | 688.629 |
| Exact Mass | 687.058960 |
| InChIKey | XKDCUJBWVGDNSH-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccccc1Br.CS(=O)(=O)O.CS(=O)(=O)O.O |
| Dimesylate Dimesylate Monohydrate |
| 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole methanesulfonate hydrate (1:2:1) |
| 1H-Indole, 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-, methanesulfonate, hydrate (1:2:1) |