Neuromedin B trifluoroacetate salt
Neuromedin B trifluoroacetate salt structure
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Common Name | Neuromedin B trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 87096-84-2 | Molecular Weight | 1132.29000 | |
| Density | 1.337 g/cm3 | Boiling Point | 1697.4ºC | |
| Molecular Formula | C52H73N15O12S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 980.3ºC | |
Use of Neuromedin B trifluoroacetate saltNeuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. |
| Name | Neuromedin B (porcine) |
|---|---|
| Synonym | More Synonyms |
| Description | Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. |
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| Related Catalog | |
| In Vitro | Potency to stimulate contraction of rat uterine smooth muscle, that is used as bioassay for isolation of Neuromedin B (NMB), is compared with Bombesin (BN). The relative potency, calculated on molar basis by taking BN as 100, is 48% for GRP and 4.9% for NMB. NMB also has contractile activity on rat stomach strip, but the potency (ratio of peptide concentration required to elicit 50% maximum response; EC50) is only 5% of BN (EC50 of BN/EC50 of NMB) and about 10% of GRP (EC50 of GRP/ EC50 of NMB)[1]. |
| In Vivo | Potencies of NMB and GRP for smooth muscle contraction of fundus in wild-type and NMB-R-deficient mice with ED50 of 14.4±2.3 (n=8) and 10.9±2.3 (n=8) in wild-type mice and NMB-R-deficient mice, respectively[1]. |
| References |
[1]. Ohki-Hamazaki H. Neuromedin B. Prog Neurobiol. 2000 Oct;62(3):297-312. |
| Density | 1.337 g/cm3 |
|---|---|
| Boiling Point | 1697.4ºC |
| Molecular Formula | C52H73N15O12S |
| Molecular Weight | 1132.29000 |
| Flash Point | 980.3ºC |
| Exact Mass | 1131.53000 |
| PSA | 464.10000 |
| LogP | 2.05180 |
| Index of Refraction | 1.613 |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |
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Expression and regulation of neuromedin B in pituitary corticotrophs of male melanocortin 2 receptor-deficient mice.
Endocrinology 155(7) , 2492-9, (2014) The hypothalamic-pituitary-adrenal (HPA) axis is a major part of the neuroendocrine system that controls responses to stress, and has an important function in the regulation of various body processes.... |
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Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts.
J. Endocrinol. 217(2) , 141-50, (2013) Neuromedin B (NMB) is a mammalian bombesin-like peptide that regulates exocrine/endocrine secretion, smooth muscle contraction, body temperature, and the proliferation of some cell types. Here, we sho... |
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Effect of potential on temperature-dependent SERS spectra of neuromedin B on Cu electrode.
Phys. Chem. Chem. Phys. 15(3) , 807-15, (2013) Adsorption of decapeptide neuromedin B (NMB) on copper electrode has been investigated by in situ surface-enhanced Raman scattering (SERS) spectroelectrochemistry in the temperature interval from 12 t... |
| GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 |
| GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 ACOH 5H2O |
| NEUROMEDIN B,PORCINE |
| GNLWATGHFM-NH2 |
| Gly-L-Asn-L-Leu-L-Trp-L-Ala-L-Thr-Gly-L-His-L-Phe-L-Met-NH2 |
| H-GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 |
| NEUROMEDIN B,PORCINE MAMMALIAN BOMBESIN-LI |
| neuromedin-B |
| Neuromedin B |
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- Product Name: Neuromedin B
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