ABT-384
Modify Date: 2025-08-26 22:53:25
ABT-384 structure
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Common Name | ABT-384 | ||
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| CAS Number | 868623-40-9 | Molecular Weight | 493.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H34F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ABT-384ABT-384 is a selective 11-β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor. ABT-384 blocks regeneration of active cortisol. ABT-384 exhibits high affinity against rodent, monkey, and human HSD-1 whit a Ki of 0.1-2.7 nM[1][2]. |
| Name | ABT-384 |
|---|
| Description | ABT-384 is a selective 11-β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor. ABT-384 blocks regeneration of active cortisol. ABT-384 exhibits high affinity against rodent, monkey, and human HSD-1 whit a Ki of 0.1-2.7 nM[1][2]. |
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| Related Catalog | |
| In Vivo | ABT-384 can be used for the research of the Cushing’s syndrome, obesity, insulin resistance, hypertension, dyslipidemia, osteoporosis, glaucoma, major depressive disorder, and Alzheimer’s disease (AD) [2] . |
| References |
| Molecular Formula | C25H34F3N5O2 |
|---|---|
| Molecular Weight | 493.56 |