Indirubin E804

Modify Date: 2024-01-03 18:21:45

Indirubin E804 structure	Common Name	Indirubin E804
	CAS Number	854171-35-0	Molecular Weight	365.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₉N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Indirubin E804

E 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.

Name	Indirubin Derivative E804

Description	E 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R Research Areas >> Cancer Research Areas >> Others
Target	IC50: 0.65 μM (IGF1R)[1].
In Vitro	Indirubin Derivative E804 is a water-soluble indirubin derivative as potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM. Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0.23 μM[1].
References	[1]. Cheng X, et al. Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962.

Molecular Formula	C₂₀H₁₉N₃O₄
Molecular Weight	365.38

DC Chemicals Limited
China
Product Name: Indirubin E804
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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