Name | 5-Iodo-indirubin-3'-monoxime |
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Description | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively[1]. |
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Related Catalog | |
Target |
GSK-3β:9 nM (IC50) Cdk5/p25:20 nM (IC50) Cdk1/cyclin B:25 nM (IC50) |
References |
Molecular Formula | C16H10IN3O2 |
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Molecular Weight | 403.17 |