H2N-PEG8-CH2CH2COO<sup>t</sup>Bu

Modify Date: 2024-01-16 10:05:25

H2N-PEG8-CH2CH2COO<sup>t</sup>Bu Structure
H2N-PEG8-CH2CH2COO<sup>t</sup>Bu structure
Common Name H2N-PEG8-CH2CH2COO<sup>t</sup>Bu
CAS Number 756526-06-4 Molecular Weight 497.62000
Density N/A Boiling Point N/A
Molecular Formula C23H47NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H2N-PEG8-CH2CH2COO<sup>t</sup>Bu


Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name amino-dPEG8.(TM).-t-butyl ester
Synonym More Synonyms

 H2N-PEG8-CH2CH2COO<sup>t</sup>Bu Biological Activity

Description Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups. WO2016207089A1.

 Chemical & Physical Properties

Molecular Formula C23H47NO10
Molecular Weight 497.62000
Exact Mass 497.32000
PSA 126.16000
LogP 1.51000

 Safety Information

Hazard Codes Xn

 Synonyms

H2N-PEG8-CH2CH2COOtBu
H2N-PEG8- CH2CH2COOtBu