H2N-PEG8-CH2CH2COO<sup>t</sup>Bu

Modify Date: 2026-07-01 20:23:38

H2N-PEG8-CH2CH2COO<sup>t</sup>Bu Structure
H2N-PEG8-CH2CH2COO<sup>t</sup>Bu structure
Common Name H2N-PEG8-CH2CH2COO<sup>t</sup>Bu
CAS Number 756526-06-4 Molecular Weight 497.62000
Density N/A Boiling Point N/A
Molecular Formula C23H47NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H2N-PEG8-CH2CH2COO<sup>t</sup>Bu


Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name amino-dPEG8.(TM).-t-butyl ester
Synonym More Synonyms

 H2N-PEG8-CH2CH2COO<sup>t</sup>Bu Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups. WO2016207089A1.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C23H47NO10
Molecular Weight 497.62000
Exact Mass 497.32000
PSA 126.16000
LogP 1.51000
InChIKey UMJVFHNJPJVDSB-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xn

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

H2N-PEG8-CH2CH2COOtBu
H2N-PEG8- CH2CH2COOtBu

 H2N-PEG8-CH2CH2COO<sup>t</sup>Bu | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of amino-dPEG8.(TM).-t-butyl ester?
A: SMILES notation of amino-dPEG8.(TM).-t-butyl ester is CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN.
Q: What English synonyms does amino-dPEG8.(TM).-t-butyl ester have?
A: English synonyms of amino-dPEG8.(TM).-t-butyl ester: H2N-PEG8-CH2CH2COOtBu, H2N-PEG8- CH2CH2COOtBu.
Q: What is the molecular weight of amino-dPEG8.(TM).-t-butyl ester?
A: Molecular weight of amino-dPEG8.(TM).-t-butyl ester is 497.62000.
Q: What is the InChIKey of amino-dPEG8.(TM).-t-butyl ester?
A: InChIKey of amino-dPEG8.(TM).-t-butyl ester is UMJVFHNJPJVDSB-UHFFFAOYSA-N.
Q: What is the molecular formula of amino-dPEG8.(TM).-t-butyl ester?
A: Molecular formula of amino-dPEG8.(TM).-t-butyl ester is C23H47NO10.
Q: What is the polar surface area (PSA) of amino-dPEG8.(TM).-t-butyl ester?
A: Polar surface area (PSA) of amino-dPEG8.(TM).-t-butyl ester is 126.16000.
Q: What is the English name of amino-dPEG8.(TM).-t-butyl ester?
A: The English name of amino-dPEG8.(TM).-t-butyl ester is amino-dPEG8.(TM).-t-butyl ester.
Q: What is the LogP of amino-dPEG8.(TM).-t-butyl ester?
A: LogP of amino-dPEG8.(TM).-t-butyl ester is 1.51000.
Q: What are the uses of amino-dPEG8.(TM).-t-butyl ester?
A: Main uses of amino-dPEG8.(TM).-t-butyl ester: Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Q: What is the CAS number of amino-dPEG8.(TM).-t-butyl ester?
A: CAS number of amino-dPEG8.(TM).-t-butyl ester is 756526-06-4.

 H2N-PEG8-CH2CH2COO<sup>t</sup>Bufactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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