Bromoacetamido-PEG8-t-butyl ester

Modify Date: 2024-01-10 12:25:16

Bromoacetamido-PEG8-t-butyl ester Structure
Bromoacetamido-PEG8-t-butyl ester structure
Common Name Bromoacetamido-PEG8-t-butyl ester
CAS Number 2055041-16-0 Molecular Weight 618.55
Density N/A Boiling Point N/A
Molecular Formula C25H48BrNO11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromoacetamido-PEG8-t-butyl ester


Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromoacetamido-PEG8-Boc
Synonym More Synonyms

 Bromoacetamido-PEG8-t-butyl ester Biological Activity

Description Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H48BrNO11
Molecular Weight 618.55

 Synonyms

MFCD29918248