VU 0134992

Modify Date: 2024-01-09 15:41:54

VU 0134992 structure	Common Name	VU 0134992
	CAS Number	755002-90-5	Molecular Weight	411.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₃₁BrN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VU 0134992

VU0134992 is a selective inward rectifier potassium (Kir) channel Kir4.1 blocker with an IC50 of 0.97 µM[1].

Name	VU0134992

Description	VU0134992 is a selective inward rectifier potassium (Kir) channel Kir4.1 blocker with an IC50 of 0.97 µM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IC50: 0.97 µM (Kir4.1)[1]
In Vitro	VU0134992 is greater than 30-fold selective for Kir4.1 over Kir1.1, Kir2.1, and Kir2.2, is weakly active toward Kir2.3, Kir6.2/SUR1, and Kir7.1, and is equally active toward Kir3.1/3.2, Kir3.1/3.4, and Kir4.2[1].
References	[1]. Kharade SV, et al. Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992. Mol Pharmacol. 2018 Aug;94(2):926-937.

Molecular Formula	C₂₀H₃₁BrN₂O₂
Molecular Weight	411.38

DC Chemicals Limited
China
Product Name: VU0134992
Price: $650.0/100mg $1200.0/250mg $2400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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