Acetyl chloride

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C2-H3-Cl-O

MOLECULAR WEIGHT :

78.50

WISWESSER LINE NOTATION :

GV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human

DOSE/DURATION :

2 ppm/1M

TOXIC EFFECTS :

Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - other changes

REFERENCE :

TGNCDL "Handbook of Organic Industrial Solvents," 2nd ed., Chicago, National Assoc. of Mutual Casualty Companies, 1961 Volume(issue)/page/year: 2,28,1961

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

910 mg/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement Lungs, Thorax, or Respiration - other changes

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(3),48,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81687 No. of Facilities: 96 (estimated) No. of Industries: 4 No. of Occupations: 7 No. of Employees: 931 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81687 No. of Facilities: 40 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 2534 (estimated) No. of Female Employees: 575 (estimated)