Acetyl chloride

Names

[ CAS No. ]:
75-36-5

[ Name ]:
Acetyl chloride

[Synonym ]:
EINECS 200-865-6
Ethanoic acid chloride
1-Chloroethanone
Ethanoylcholride
MFCD00000719
acetic acid chloride
ACETYLCLORIDE
CH3COCl
acetylchloride313
Acetic chloride
Acetylchlorid
Acetyl chloride
ethanoyl chloride
acid chloride
acetochlor [ANSI, WSSA]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
46.0±3.0 °C at 760 mmHg

[ Melting Point ]:
-112 °C

[ Molecular Formula ]:
C₂H₃ClO

[ Molecular Weight ]:
78.498

[ Flash Point ]:
4.4±0.0 °C

[ Exact Mass ]:
77.987244

[ PSA ]:
17.07000

[ LogP ]:
0.46

[ Vapour density ]:
2.7 (vs air)

[ Vapour Pressure ]:
341.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.379

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AO6390000

CHEMICAL NAME :: Acetyl chloride

CAS REGISTRY NUMBER :: 75-36-5

BEILSTEIN REFERENCE NO. :: 0605303

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C2-H3-Cl-O

MOLECULAR WEIGHT :: 78.50

WISWESSER LINE NOTATION :: GV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 2 ppm/1M

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - other changes

REFERENCE :: TGNCDL "Handbook of Organic Industrial Solvents," 2nd ed., Chicago, National Assoc. of Mutual Casualty Companies, 1961 Volume(issue)/page/year: 2,28,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 910 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement Lungs, Thorax, or Respiration - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(3),48,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81687 No. of Facilities: 96 (estimated) No. of Industries: 4 No. of Occupations: 7 No. of Employees: 931 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81687 No. of Facilities: 40 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 2534 (estimated) No. of Female Employees: 575 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302-H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R11;R14;R34

[ Safety Phrases ]:
S9-S16-S26-S45-S1/2

[ RIDADR ]:
UN 1717 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
AO6390000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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