monochloroethane

Modify Date: 2025-08-21 11:41:42

monochloroethane structure	Common Name	monochloroethane
	CAS Number	75-00-3	Molecular Weight	64.514
	Density	0.9±0.1 g/cm3	Boiling Point	12.7±3.0 °C at 760 mmHg
	Molecular Formula	C₂H₅Cl	Melting Point	−139 °C(lit.)
	MSDS	Chinese	Flash Point	-56.7±2.8 °C
	Symbol	GHS02, GHS07, GHS08	Signal Word	Danger

Name	chloroethane
Synonym	More Synonyms

Density	0.9±0.1 g/cm3
Boiling Point	12.7±3.0 °C at 760 mmHg
Melting Point	−139 °C(lit.)
Molecular Formula	C₂H₅Cl
Molecular Weight	64.514
Flash Point	-56.7±2.8 °C
Exact Mass	64.007980
LogP	1.50
Vapour density	2.22 (vs air)
Vapour Pressure	1169.9±0.0 mmHg at 25°C
Index of Refraction	1.362
Stability	Stable. Highly flammable - may form explosive mixtures with air. Incompatible with strong oxidizing agents, alkali metals and their alloys.

monochloroethane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH7525000

CHEMICAL NAME :: Ethane, chloro-

CAS REGISTRY NUMBER :: 75-00-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 56

MOLECULAR FORMULA :: C2-H5-Cl

MOLECULAR WEIGHT :: 64.52

WISWESSER LINE NOTATION :: G2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 152 gm/m3/2H

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Behavioral - general anesthetic Blood - hemorrhage

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 146 gm/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 40000 ppm/45M

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/m3/2H/60D-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Immunological Including Allergic - decrease in cellular immune response

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 570 mg/m3/4H/26W-I

TOXIC EFFECTS :: Liver - liver function tests impaired Immunological Including Allergic - decrease in cellular immune response Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5000 ppm/23H/11D-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15000 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15000 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - uterine tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 60 mg/m3/4H

SEX/DURATION :: male 26 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 322,33,1994 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 264 mg/m3 (100 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 TOXICOLOGY REVIEW AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 40(3),A46,1979 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1000 ppm (2600 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,106,1971 OSHA PEL (Gen Indu):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1000 ppm (2640 mg/m3) JAN 1993 OEL-DENMARK:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-FINLAND:TWA 500 ppm (1300 mg/m3);STEL 625 ppm (1625 mg/m3) JAN 1993 OEL-FRANCE:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-GERMANY:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-HUNGARY:TWA 100 mg/m3;STEL 300 mg/m3 JAN 1993 OEL-JAPAN:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-POLAND:TWA 200 mg/m3 JAN 1993 OEL-RUSSIA:TWA 1000 ppm;STEL 50 mg/m3 JAN 1993 OEL-SWEDEN:TWA 500 ppm (1300 mg/m3);STEL 700 ppm (1900 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-TURKEY:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1000 ppm (2600 mg/m3);STEL 1250 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MONOCHLOROETHANE-air:Handle with caution REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 31970 No. of Facilities: 6154 (estimated) No. of Industries: 80 No. of Occupations: 66 No. of Employees: 96531 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 31970 No. of Facilities: 766 (estimated) No. of Industries: 12 No. of Occupations: 47 No. of Employees: 49210 (estimated) No. of Female Employees: 35368 (estimated)

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H315-H351
Supplemental HS	May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.
Precautionary Statements	P210-P281
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes	F+:Extremelyflammable;Xn:Harmful;
Risk Phrases	R12;R40;R52/53
Safety Phrases	S9-S16-S33-S36/37-S61-S45-S7-S29-S36/37/39-S26-S53
RIDADR	UN 1993 3/PG 2
WGK Germany	2
RTECS	KH7525000
Hazard Class	2.1
HS Code	2903110000

Precursor 9
CAS#:64-17-5 Ethanol CAS#:87463-00-1 O-ethyl N-methy... CAS#:74-96-4 Bromoethane CAS#:141-78-6 ethyl acetate
CAS#:65039-09-0 1-Ethyl-3-methy... CAS#:60-29-7 Diethyl ether CAS#:103-80-0 Phenylacetyl ch... CAS#:93-89-0 Ethyl benzoate
CAS#:75-03-6 Ethyl iodide
DownStream 10
CAS#:105-93-1 N-ethylbis(2-et... CAS#:24426-21-9 1,2-Ethanediami... CAS#:4432-87-5 N-ethyl-N'-[2-(... CAS#:137554-10-0 N'-[2-(ethylami...
CAS#:5336-57-2 2-Ethyl-2-pheny... CAS#:3264-67-3 TRIETHYLOXONIUM... CAS#:557-66-4 Ethylamine hydr... CAS#:5668-93-9 3-Ethylbiphenyl
CAS#:699-91-2 2-Hydroxy-3-met... CAS#:488-17-5 3-Methylcatechol

HS Code	2903110000
Summary	2903110000 chloroethane。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0%

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

Eur. J. Med. Chem. 43 , 714-40, (2008)

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...

Identification of Dehalobacter reductive dehalogenases that catalyse dechlorination of chloroform, 1,1,1-trichloroethane and 1,1-dichloroethane.

Philos. Trans. R. Soc. Lond., B, Biol. Sci. 368(1616) , 20120318, (2013)

Two novel reductive dehalogenases (RDases) that are highly similar to each other but catalyse distinct dechlorination reactions were identified from Dehalobacter-containing mixed cultures. These two R...

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

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EINECS 200-830-5

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: monochloroethane
Price: Check
Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chloroethane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: chloroethane
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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