HO-PEG11-OH

Modify Date: 2024-01-14 16:41:05

HO-PEG11-OH Structure
HO-PEG11-OH structure
Common Name HO-PEG11-OH
CAS Number 6809-70-7 Molecular Weight 502.59300
Density 1.116g/cm3 Boiling Point 571.4ºC at 760 mmHg
Molecular Formula C22H46O12 Melting Point N/A
MSDS N/A Flash Point 299.3ºC

 Use of HO-PEG11-OH


HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 HO-PEG11-OH Biological Activity

Description HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.116g/cm3
Boiling Point 571.4ºC at 760 mmHg
Molecular Formula C22H46O12
Molecular Weight 502.59300
Flash Point 299.3ºC
Exact Mass 502.29900
PSA 132.76000
Index of Refraction 1.465

 Safety Information

HS Code 2909499000

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

EINECS 229-884-8
3,6,9,12,15,18,21,24,27,30-Decaoxadotriacontane-1,32-diol
Undecaethylene glycol
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