HO-PEG24-OH

Modify Date: 2024-01-11 18:46:30

HO-PEG24-OH Structure
HO-PEG24-OH structure
Common Name HO-PEG24-OH
CAS Number 2243942-52-9 Molecular Weight 1075.28
Density N/A Boiling Point N/A
Molecular Formula C48H98O25 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HO-PEG24-OH


HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name HO-PEG24-OH
Synonym More Synonyms

 HO-PEG24-OH Biological Activity

Description HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C48H98O25
Molecular Weight 1075.28

 Synonyms

MFCD28976705