HO-PEG16-OH

Modify Date: 2024-01-15 08:18:50

HO-PEG16-OH Structure
HO-PEG16-OH structure
Common Name HO-PEG16-OH
CAS Number 6812-36-8 Molecular Weight 722.85600
Density 1.116g/cm3 Boiling Point 714.7ºC at 760 mmHg
Molecular Formula C32H66O17 Melting Point N/A
MSDS N/A Flash Point 386.1ºC

 Use of HO-PEG16-OH


HO-PEG16-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 HO-PEG16-OH Biological Activity

Description HO-PEG16-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.116g/cm3
Boiling Point 714.7ºC at 760 mmHg
Molecular Formula C32H66O17
Molecular Weight 722.85600
Flash Point 386.1ºC
Exact Mass 722.43000
PSA 178.91000
Index of Refraction 1.466

 Synonyms

hexadecaethylene glycol
EINECS 229-886-9
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-diol
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