4-Hydroxybenzamide

Modify Date: 2024-01-17 16:07:29

4-Hydroxybenzamide Structure
4-Hydroxybenzamide structure
Common Name 4-Hydroxybenzamide
CAS Number 619-57-8 Molecular Weight 137.136
Density 1.3±0.1 g/cm3 Boiling Point 345.3±25.0 °C at 760 mmHg
Molecular Formula C7H7NO2 Melting Point 161-162 °C(lit.)
MSDS Chinese USA Flash Point 162.6±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-Hydroxybenzamide


4-Hydroxybenzamide, found in the herb of Berberis pruinosa, is a known natural product that has potential to slow down the progression of atherosclerosis[1].

 Names

Name 4-Hydroxybenzamide
Synonym More Synonyms

 4-Hydroxybenzamide Biological Activity

Description 4-Hydroxybenzamide, found in the herb of Berberis pruinosa, is a known natural product that has potential to slow down the progression of atherosclerosis[1].
Related Catalog
References

[1]. Habsah Mohamad, et al. Potential Secondary Metabolites from Marine Sponge Aaptos aaptos for Atherosclerosis and Vibriosis Treatments. Natural Product Communications. 2017. 12(8):1227-1230.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 345.3±25.0 °C at 760 mmHg
Melting Point 161-162 °C(lit.)
Molecular Formula C7H7NO2
Molecular Weight 137.136
Flash Point 162.6±23.2 °C
Exact Mass 137.047684
PSA 63.32000
LogP 0.25
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.612

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2924299090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles9

More Articles
Influence of Secondary Interactions on the Structure, Sublimation Thermodynamics, and Solubility of Salicylate:4-Hydroxybenzamide Cocrystals. Combined Experimental and Theoretical Study.

J. Phys. Chem. B 119 , 10466-77, (2015)

Cocrystal screening of 4-hydroxybenzamide with a number of salicylates (salicylic acid, SA; 4-aminosalicylic acid, PASA; acetylsalicylic acid, ASA; and salicylsalicylic acid, SSA) was conducted to con...

Synthesis and protein kinase C inhibitory activities of balanol analogs with replacement of the perhydroazepine moiety.

J. Med. Chem. 40(2) , 226-35, (1997)

Balanol is a potent protein kinase C (PKC) inhibitor that is structurally composed of a benzophenone diacid, a 4-hydroxybenzamide, and a perhydroazepine ring. A number of balanol analogs in which the ...

Energetics of the O-H bond and of intramolecular hydrogen bonding in HOC6H4C(O)Y (Y = H, CH3, CH2CH=CH2, C[triple bond]CH, CH2F, NH2, NHCH3, NO2, OH, OCH3, OCN, CN, F, Cl, SH, and SCH3) compounds.

J. Phys. Chem. A 112(40) , 10029-39, (2008)

The energetics of the phenolic O-H bond in a series of 2- and 4-HOC 6H 4C(O)Y (Y = H, CH3, CH 2CH=CH2, C[triple bond]CH, CH2F, NH2, NHCH 3, NO2, OH, OCH3, OCN, CN, F, Cl, SH, and SCH3) compounds and o...

 Synonyms

4-Hydroxybenzamide
Benzamide,4-hydroxy
EINECS 210-602-7
4-hydroxy-benzamide
4-Hydroxybenzolcarboxamid
MFCD00007997
4-hydroxyphenylformamide
4-Hydroxy-benzoesaeure-amid
Benzamide, 4-hydroxy-
para-hydroxybenzamide
P-HYDROXYBENZAMIDE
4-hydroxy-benzoic acid amide
4-Hydroxy-benzamid
4-Hydroxybenzamide (p-Hydroxybenzamide)
Benzamide,p-hydroxy
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