Dideoxy-amanitin
Modify Date: 2025-10-15 18:14:41
Dideoxy-amanitin structure
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Common Name | Dideoxy-amanitin | ||
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| CAS Number | 58255-46-2 | Molecular Weight | 886.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C39H54N10O12S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dideoxy-amanitinDideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM[1]. |
| Name | Dideoxy-amanitin |
|---|
| Description | Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM[1]. |
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| Related Catalog | |
| In Vitro | Dideoxy-amanitin (compound 2; 0.078-20 μM; 24 h) has cell cytotoxicity in CHO (Chinese hamster ovary) cells with an IC50 value of 0.3 μM[1]. Cell Viability Assay[1] Cell Line: CHO (Chinese hamster ovary) cells Concentration: 0.078-20 μM Incubation Time: 24 hours Result: Decreased cell proliferation in a dose-depengdent manner. |
| Molecular Formula | C39H54N10O12S |
|---|---|
| Molecular Weight | 886.97 |
| InChIKey | RXGJTYFDKOHJHK-KFGVHZSZSA-N |
| SMILES | CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4ccccc34)SCC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(O)CO)C(=O)N2 |