5α-Dihydroprogesterone

Modify Date: 2025-09-01 09:57:24

5α-Dihydroprogesterone structure	Common Name	5α-Dihydroprogesterone
	CAS Number	566-65-4	Molecular Weight	316.478
	Density	1.0±0.1 g/cm3	Boiling Point	429.2±38.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₃₂O₂	Melting Point	204 °C
	MSDS	N/A	Flash Point	160.3±23.8 °C

Use of 5α-Dihydroprogesterone

5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

Name	5α-pregnane-3,20-dione
Synonym	More Synonyms

Description	5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Related Catalog	Research Areas >> Endocrinology Natural Products >> Flavonoids
Target	Human Endogenous Metabolite
In Vitro	5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells[1].
References	[1]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.

Density	1.0±0.1 g/cm3
Boiling Point	429.2±38.0 °C at 760 mmHg
Melting Point	204 °C
Molecular Formula	C₂₁H₃₂O₂
Molecular Weight	316.478
Flash Point	160.3±23.8 °C
Exact Mass	316.240234
PSA	34.14000
LogP	4.31
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.516

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4157150

CHEMICAL NAME :: 5-beta-Pregnane-3,20-dione

CAS REGISTRY NUMBER :: 566-65-4

BEILSTEIN REFERENCE NO. :: 2058506

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H32-O2

MOLECULAR WEIGHT :: 316.53

WISWESSER LINE NOTATION :: L E5 B666 OVTJ A1 E1 FV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968

Hazard Codes	Xi
WGK Germany	3
RTECS	TU4157150

Precursor 9
CAS#:57-83-0 Progesterone CAS#:516-53-0 (20R)-5alpha-pr... CAS#:6170-12-3 Pregnane-3,20-d... CAS#:516-55-2 Alloepipregnanolone
CAS#:7680-01-5 3β-methoxy-5-α-... CAS#:145-13-1 Pregnenolone CAS#:566-58-5 (3R,5S,8R,9S,10... CAS#:516-54-1 5alpha-Pregnan-...
CAS#:1778-02-5 3β-acetoxy-preg...
DownStream 6
CAS#:567-02-2 THDOC CAS#:38398-32-2 Ganaxolone CAS#:1264737-31-6 1-((3S,5S,8R,9S... CAS#:516-55-2 Alloepipregnanolone
CAS#:516-54-1 5alpha-Pregnan-... CAS#:566-57-4 5-ALPHA-PREGNAN...

5a-Dihydroprogesterone

4-07-00-02199 (Beilstein Handbook Reference)

Pregnane-3,20-dione, (5-α)- (9CI)

5alpha-Pregnan-3,20-dione

MFCD00067132

Allopregnane-3,20-dione

(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

UNII:98G4S1OH0Z

5α-pregnane-3,20-dione

(5α)-Pregnane-3,20-dione

Pregnane-3,20-dione

5α-dihydroprogesterone

EINECS 209-297-3

Allopregnan-3,20-dione

3,20-Allopregnanedione

5alpha-pregnane-3,20-dione

3,20-Dioxo-5a-pregnane

5a-Pregnan-3,20-dione

Pregnane-3,20-dione, (5α)-

Pregnane-3,20-dione, (5α)- (9CI)

3,20-Dioxo-5alpha-pregnane

5-α-pregnane-3,20-dione

allopregnandione

5alpha-Dihydroprogesterone

5a-Pregnane-3,20-dione

5α-Pregnane-3,20-dione (8CI)

(5Alpha)-Pregnane-3,20-dione

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China
Product Name: 5α-Dihydroprogesterone
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China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-alpha-Dihydroprogesterone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 566-65-4 5-alpha-Dihydroprogesterone
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: ￥800/100 mg

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