Maleimide

Modify Date: 2024-01-02 18:22:48

Maleimide Structure
Maleimide structure
Common Name Maleimide
CAS Number 541-59-3 Molecular Weight 97.072
Density 1.4±0.1 g/cm3 Boiling Point 264.4±23.0 °C at 760 mmHg
Molecular Formula C4H3NO2 Melting Point 91-93 °C(lit.)
MSDS Chinese USA Flash Point 113.7±22.6 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name maleimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 264.4±23.0 °C at 760 mmHg
Melting Point 91-93 °C(lit.)
Molecular Formula C4H3NO2
Molecular Weight 97.072
Flash Point 113.7±22.6 °C
Exact Mass 97.016380
PSA 46.17000
LogP -0.69
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.606
Storage condition Refrigerator
Water Solubility SOLUBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ON4800000
CHEMICAL NAME :
Maleimide
CAS REGISTRY NUMBER :
541-59-3
BEILSTEIN REFERENCE NO. :
0106910
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C4-H3-N-O2
MOLECULAR WEIGHT :
97.08
WISWESSER LINE NOTATION :
T5VMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(11),109,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7766 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - hemorrhage Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - other changes
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,151,1978 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
750 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
3100 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H314-H317
Precautionary Statements P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T:Toxic;
Risk Phrases R25;R36/37/38;R43
Safety Phrases S26-S36/37/39-S45-S37/39-S28A
RIDADR UN 2923 8/PG 2
WGK Germany 3
RTECS ON4800000
Packaging Group III
Hazard Class 8
HS Code 29251995

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles174

More Articles
Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion.

Nat. Commun. 5 , 5263, (2014)

Proteins are co-translationally inserted into the bacterial plasma membrane via the SecYEG translocon by lateral release of hydrophobic transmembrane segments into the phospholipid bilayer. The trigge...

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay.

Antimicrob. Agents Chemother. 59(1) , 193-205, (2014)

Gram-negative bacteria are formidable pathogens because their cell envelope presents an adaptable barrier to environmental and host-mediated challenges. The stress response pathway controlled by the a...

Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor.

Biochem. Biophys. Res. Commun. 456(1) , 116-21, (2014)

G protein-coupled receptors (GPCRs) represent the largest family of transmembrane signaling proteins, and they are considered major targets of approximately half of all therapeutic agents. Human melan...

 Synonyms

maleic acid imide
monomaleimide
Maleic imide
EINECS 208-787-4
1H-Pyrrole-2.5-dione
3-pyrroline-2,5-dione
Maleimide
Maleinimide
pyrroline-2,5-dion
2,5-Pyrroledione
1H-Pyrrole-2,5-dione
N-hydroxysuccinimide
MFCD00005494
Pyrrole-2,5-dione
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Maleimide suppliers

Maleimide price